Could everyday foods shape a healthier gut in babies? New research says yes

29 April 2025 - New research has identified common foods that could play a key role in shaping a baby’s gut microbiome, with potential long-term health benefits.  

The study, led by Riddet Institute PhD fellow Vitor Geniselli da Silva, examined how different foods interact with gut bacteria using baby faecal samples. It found that berries and black beans promote the growth of beneficial bacteria and the production of short-chain fatty acids, both linked to better gut health.  

The research, conducted by a team including Prof Warren McNabb, Prof Nicole Roy, Prof Clare Wall, Dr Jane Mullaney, Dr Nick Smith, and Mr Callum Tatton evaluated 14 individual foods, including infant formula, meats, fruits, vegetables, and legumes, along with various food-infant formula combinations to reflect real-life infant feeding patterns. The goal was to understand how these foods affect babies’ gut bacteria and the organic acids they produce in controlled laboratory conditions.  

Among the key findings: 

• Berries (blackcurrants, strawberries, and raspberries), when tested individually, increased the production of acetate and propionate — short-chain fatty acids associated with gut health. They also boosted the presence of Parabacteroides, a bacterial genus known to support gut function 

• Black beans combined with infant formula increased the production of butyrate and the growth of Clostridium sensu stricto 1, both of which contribute to a balanced gut microbiota 

These changes in microbial function and composition indicate a transition from the infant gut microbiota to the adult one, which is more stable. Therefore, these foods may help establish beneficial gut microbiota from early on, contributing to promoting human health. 

“These findings suggest that certain everyday foods, alone or in combination with infant formula, can positively influence the development of gut bacteria in babies,” says Vitor. “This could play a key role in early nutrition and diet recommendations.”  

While the study was conducted in a controlled laboratory model and does not fully replicate the complexity of the human body, it lays the groundwork for future clinical trials. Researchers emphasise that more studies are needed to confirm these results in real-world conditions. 

“This research opens exciting possibilities for infant nutrition,” added Prof Warren McNabb. “If future studies confirm these benefits, they may be able to guide parents and healthcare professionals on how to optimise gut health from infancy.”  

Findings have been published in the journal Food & Function under the title “Complementary foods in infants: an in vitro study of the faecal microbial composition and organic acid production”